Chinese Scientists Achieve Major Breakthrough in Epilepsy Treatment
Brain
Chinese scientists have successfully tested an experimental treatment that uses genetic engineering and a drug-activated molecular switch to suppress seizures in patients with drug-resistant epilepsy, according to research published in the New England Journal of Medicine.Breakthrough results: Three patients aged 28–37 experienced an average 92.6% reduction in seizures just two months after treatment.How it works: Researchers injected a modified viral vector into the hippocampus, making targeted neurons respond to low doses of clozapine, a drug that suppresses abnormal electrical activity.Long-lasting effects: Two patients remained seizure-free during extended follow-up, while the third regained seizure control after restarting medication following an interruption.
The world’s first human trial of this approach could open a new treatment pathway for millions of people with drug-resistant epilepsy, potentially controlling seizures without removing brain tissue.
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